Assay Detail
Binding
CHEMBL4430969
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant HIV1 RT
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 reverse transcriptase (CHEMBL247) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Advances in rationally designed dual inhibitors of HIV-1 reverse transcriptase and integrase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.02 | 4.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4587138 | — | — | 1 | 4.02 |
| CHEMBL4525601 | — | — | 1 | - |
| CHEMBL4549316 | — | — | 1 | - |
| CHEMBL4461731 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4587138 | — | IC50 | = | 95090.0 | nM | 4.02 |
| CHEMBL4525601 | — | IC50 | = | 113100.0 | nM | - |
| CHEMBL4549316 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4461731 | — | IC50 | > | 200000.0 | nM | - |