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Assay Detail

CHEMBL4431089

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of soluble guanylate cyclase (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Soluble guanylate cyclase (CHEMBL2111348)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

Analysis of quinolinequinone reactivity, cytotoxicity, and anti-HIV-1 properties.
Alfadhli A, Mack A, Harper L, Berk S, Ritchie C, Barklis E.
Bioorg Med Chem (2016) 24 : 5618 -5625
PubMed 27663546 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL312487 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL312487 IC50 = 1000.0 nM 6.00