Assay Detail
Binding
CHEMBL4431535
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Dengue virus 3 NS2B-NS3 protease expressed in Escherichia coli using Abz-RRRRSAG-nY-NH2 as substrate preincubated for 20 mins followed by addition of substrate measured after 60 mins by fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | dengue virus type 3 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The Medicinal Chemistry of Dengue Virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.61 | 4.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3344310 | — | — | 1 | 4.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3344310 | — | Ki | = | 24400.0 | nM | 4.61 |