Assay Detail
Binding
CHEMBL4431691
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Modulation of gamma-secretase (unknown origin) assessed as inhibition of amyloid beta 42 production
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Gamma Secretase Modulators: New Alzheimer's Drugs on the Horizon?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.15 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4209316 | — | — | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4209316 | — | EC50 | = | 7.0 | nM | 8.15 |