Assay Detail
Binding
CHEMBL4432674
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of protease activity of Clostridium botulinum BoNT/A using N(K)-acetyl)-SNKTRIDEANQRATKML-carboxamide as substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Clostridium botulinum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Botulinum neurotoxin type A (CHEMBL5192) ↗| Type | SINGLE PROTEIN |
| Organism | Clostridium botulinum |
Publication
Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.52 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4474592 | — | — | 1 | 7.39 |
| CHEMBL1933864 | — | — | 1 | 6.48 |
| CHEMBL501525 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4474592 | — | Ki | = | 41.0 | nM | 7.39 |
| CHEMBL1933864 | — | Ki | = | 330.0 | nM | 6.48 |
| CHEMBL501525 | — | Ki | = | 2000.0 | nM | 5.70 |