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Assay Detail

CHEMBL4432675

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Binding
Inhibition of Clostridium botulinum BoNT/A light chain using SNAP-25 as substrate by LC/MS analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Clostridium botulinum
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Botulinum neurotoxin type A (CHEMBL5192)
Type SINGLE PROTEIN
Organism Clostridium botulinum

Publication

Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity.
Zhou Y, McGillick BE, Teng YG, Haranahalli K, Ojima I, Swaminathan S, Rizzo RC.
Bioorg Med Chem (2016) 24 : 4875 -4889
PubMed 27543389 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.16 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL29660 CHICORIC ACID 1 6.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL29660 CHICORIC ACID Ki = 700.0 nM 6.16