Assay Detail
Binding
CHEMBL4433389
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Inhibition of HO-2 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.00 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4166126 | — | — | 1 | 6.34 |
| CHEMBL482686 | — | — | 1 | 5.66 |
| CHEMBL539857 | — | — | 1 | - |
| CHEMBL1187207 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4166126 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL482686 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL539857 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1187207 | — | IC50 | > | 100000.0 | nM | - |