Assay Detail
Functional
CHEMBL4479324
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiinvasive activity against human MDA-MB-231 cells measured after 48 hrs by transwell invasion assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.42 | 5.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4561852 | — | — | 1 | 5.59 |
| CHEMBL4165149 | — | — | 1 | 5.57 |
| CHEMBL4582650 | — | — | 1 | 5.44 |
| CHEMBL3415305 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4561852 | — | IC50 | = | 2586.0 | nM | 5.59 |
| CHEMBL4165149 | — | IC50 | = | 2679.0 | nM | 5.57 |
| CHEMBL4582650 | — | IC50 | = | 3632.0 | nM | 5.44 |
| CHEMBL3415305 | — | IC50 | = | 8699.0 | nM | 5.06 |