Assay Detail
Binding
CHEMBL4480505
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Inhibition of human MAOA
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of monoamine oxidase inhibitors by medicinal chemistry approaches.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.00 | 5.60 |
| Ki | 1 | 6.85 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4572140 | — | — | 1 | 6.85 |
| CHEMBL294264 | PURPURIN | — | 1 | 5.60 |
| CHEMBL4527294 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4572140 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL294264 | PURPURIN | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL4527294 | — | IC50 | = | 39740.0 | nM | 4.40 |