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Assay Detail

CHEMBL4480532

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of soyabean 5-LOX after 5 mins by spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Glycine max
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Rationally synthesized coumarin based pyrazolines ameliorate carrageenan induced inflammation through COX-2/pro-inflammatory cytokine inhibition.
Chandel P, Kumar A, Singla N, Kumar A, Singh G, Gill RK.
Medchemcomm (2019) 10 : 421 -430
PubMed 30996860 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.92 4.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1258747 1 4.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1258747 IC50 = 12000.0 nM 4.92