Assay Detail
Functional
CHEMBL4480802
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Cytotoxicity against mouse 4T1 cells after 72 hrs by MTT assay
57
Total Activities
57
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | 4T1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and anticancer evaluation of new lipophilic 1,2,4 and 1,3,4-oxadiazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 57 | 4.79 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL178 | DAUNORUBICIN | 4.0 | 1 | 6.52 |
| CHEMBL4537958 | — | — | 1 | 5.80 |
| CHEMBL4583999 | — | — | 1 | 5.72 |
| CHEMBL4585976 | — | — | 1 | 5.59 |
| CHEMBL4579706 | — | — | 1 | 5.51 |
| CHEMBL4567283 | — | — | 1 | 5.50 |
| CHEMBL4538414 | — | — | 1 | 5.45 |
| CHEMBL4545028 | — | — | 1 | 5.44 |
| CHEMBL4564492 | — | — | 1 | 5.28 |
| CHEMBL4543692 | — | — | 1 | 5.17 |
| CHEMBL4534874 | — | — | 1 | 5.09 |
| CHEMBL4529515 | — | — | 1 | 5.09 |
| CHEMBL4570866 | — | — | 1 | 5.05 |
| CHEMBL4560517 | — | — | 1 | 4.96 |
| CHEMBL4586733 | — | — | 1 | 4.92 |
| CHEMBL4572453 | — | — | 1 | 4.90 |
| CHEMBL4562698 | — | — | 1 | 4.77 |
| CHEMBL4525278 | — | — | 1 | 4.76 |
| CHEMBL4575358 | — | — | 1 | 4.70 |
| CHEMBL4566444 | — | — | 1 | 4.68 |
| CHEMBL4585342 | — | — | 1 | 4.66 |
| CHEMBL4549285 | — | — | 1 | 4.65 |
| CHEMBL4547329 | — | — | 1 | 4.65 |
| CHEMBL4539509 | — | — | 1 | 4.62 |
| CHEMBL4520590 | — | — | 1 | 4.61 |
| CHEMBL4513746 | — | — | 1 | 4.58 |
| CHEMBL4554581 | — | — | 1 | 4.53 |
| CHEMBL4576092 | — | — | 1 | 4.46 |
| CHEMBL4513417 | — | — | 1 | 4.37 |
| CHEMBL4539974 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL178 | DAUNORUBICIN | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4537958 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4583999 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL4585976 | — | IC50 | = | 2550.0 | nM | 5.59 |
| CHEMBL4579706 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL4567283 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL4538414 | — | IC50 | = | 3550.0 | nM | 5.45 |
| CHEMBL4545028 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL4564492 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL4543692 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL4534874 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL4529515 | — | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL4570866 | — | IC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL4560517 | — | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL4586733 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL4572453 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL4562698 | — | IC50 | = | 17100.0 | nM | 4.77 |
| CHEMBL4525278 | — | IC50 | = | 17500.0 | nM | 4.76 |
| CHEMBL4575358 | — | IC50 | = | 20100.0 | nM | 4.70 |
| CHEMBL4566444 | — | IC50 | = | 21100.0 | nM | 4.68 |
| CHEMBL4585342 | — | IC50 | = | 21800.0 | nM | 4.66 |
| CHEMBL4549285 | — | IC50 | = | 22400.0 | nM | 4.65 |
| CHEMBL4547329 | — | IC50 | = | 22300.0 | nM | 4.65 |
| CHEMBL4539509 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL4520590 | — | IC50 | = | 24400.0 | nM | 4.61 |
| CHEMBL4513746 | — | IC50 | = | 26400.0 | nM | 4.58 |
| CHEMBL4554581 | — | IC50 | = | 29600.0 | nM | 4.53 |
| CHEMBL4576092 | — | IC50 | = | 34700.0 | nM | 4.46 |
| CHEMBL4513417 | — | IC50 | = | 42700.0 | nM | 4.37 |
| CHEMBL4539974 | — | IC50 | = | 45100.0 | nM | 4.35 |
| CHEMBL4565669 | — | IC50 | = | 54600.0 | nM | 4.26 |
| CHEMBL4584654 | — | IC50 | = | 59600.0 | nM | 4.22 |
| CHEMBL4541668 | — | IC50 | = | 62200.0 | nM | 4.21 |
| CHEMBL4560572 | — | IC50 | = | 66800.0 | nM | 4.17 |
| CHEMBL4589665 | — | IC50 | = | 68100.0 | nM | 4.17 |
| CHEMBL4537353 | — | IC50 | = | 82600.0 | nM | 4.08 |
| CHEMBL4543578 | — | IC50 | = | 83700.0 | nM | 4.08 |
| CHEMBL4546443 | — | IC50 | = | 82600.0 | nM | 4.08 |
| CHEMBL4543455 | — | IC50 | = | 82300.0 | nM | 4.08 |
| CHEMBL4533079 | — | IC50 | = | 92300.0 | nM | 4.04 |
| CHEMBL4538065 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4578884 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4549815 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4577045 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4569063 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4555595 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4483810 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4554732 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4540413 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4533020 | — | IC50 | > | 100000.0 | nM | - |