Assay Detail
Binding
CHEMBL4481154
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli by DCIP staining-based spectrophotometric analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
1,2,4-Triazolo[1,5-a]pyrimidines in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.35 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4557830 | — | — | 1 | 7.85 |
| CHEMBL1956285 | DSM-265 | 2.0 | 1 | 7.48 |
| CHEMBL475813 | — | — | 1 | 7.33 |
| CHEMBL1784577 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4557830 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL1956285 | DSM-265 | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL475813 | — | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL1784577 | — | IC50 | = | 190.0 | nM | 6.72 |