Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4481817

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to p300 CH1 domain (unknown origin) by fluorescence anisotropy competition assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone acetyltransferase p300 (CHEMBL3784)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Advances in inhibition of protein-protein interactions targeting hypoxia-inducible factor-1 for cancer therapy.
Li J, Xi W, Li X, Sun H, Li Y.
Bioorg Med Chem (2019) 27 : 1145 -1158
PubMed 30819620 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.16 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4524475 1 6.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4524475 Kd = 690.0 nM 6.16