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Assay Detail

CHEMBL4481945

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human CK2 using HRRRDDD-SDDD-NH2 as substrate after 30 mins by ADP-Glo reagent based luminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Casein kinase 2 (CHEMBL3832943)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Inhibitory Properties of ATP-Competitive Coumestrol and Boldine Are Correlated to Different Modulations of CK2 Flexibility.
Battistutta R, Lolli G.
J Nat Prod (2019) 82 : 1014 -1018
PubMed 30840451 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL30707 COUMESTROL 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL30707 COUMESTROL IC50 = 200.0 nM 6.70