Assay Detail
Functional
CHEMBL4482067
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Cytotoxicity against human A549 cells after 72 hrs by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Conolodinines A-D, Aspidosperma- Aspidosperma Bisindole Alkaloids with Antiproliferative Activity from Tabernaemontana corymbosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.20 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL506768 | CONOPHYLLINE | — | 1 | 5.50 |
| CHEMBL2409161 | CONOFOLINE | — | 1 | 5.09 |
| CHEMBL220132 | — | — | 1 | 5.00 |
| CHEMBL4591538 | — | — | 1 | - |
| CHEMBL4520068 | — | — | 1 | - |
| CHEMBL4587015 | — | — | 1 | - |
| CHEMBL4589207 | — | — | 1 | - |
| CHEMBL4520335 | — | — | 1 | - |
| CHEMBL4524874 | — | — | 1 | - |
| CHEMBL4580115 | — | — | 1 | - |
| CHEMBL4532641 | — | — | 1 | - |
| CHEMBL4087281 | — | — | 1 | - |
| CHEMBL4552198 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL506768 | CONOPHYLLINE | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL2409161 | CONOFOLINE | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL220132 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4591538 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4520068 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4587015 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4589207 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4520335 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4524874 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4580115 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4532641 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4087281 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4552198 | — | IC50 | > | 10000.0 | nM | - |