Assay Detail
ADMET
CHEMBL4482070
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Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MRC5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Conolodinines A-D, Aspidosperma- Aspidosperma Bisindole Alkaloids with Antiproliferative Activity from Tabernaemontana corymbosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.42 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4524874 | — | — | 1 | 5.82 |
| CHEMBL4580115 | — | — | 1 | 5.40 |
| CHEMBL4532641 | — | — | 1 | 5.25 |
| CHEMBL4087281 | — | — | 1 | 5.21 |
| CHEMBL4589207 | — | — | 1 | - |
| CHEMBL4552198 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4524874 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL4580115 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL4532641 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL4087281 | — | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL4589207 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4552198 | — | IC50 | > | 10000.0 | nM | - |