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Assay Detail

CHEMBL4482467

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimigratory activity against human MDA-MB-231 cells assessed as inhibition of cell migration incubated for 6 hrs by crystal violet staining based Boyden-Chamber cell migration assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Methods for inhibiting fascin
(2014)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.61 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1540929 1 4.70
CHEMBL4539339 1 4.60
CHEMBL1188627 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1540929 IC50 = 20000.0 nM 4.70
CHEMBL4539339 IC50 = 25000.0 nM 4.60
CHEMBL1188627 IC50 = 30000.0 nM 4.52