Assay Detail
Binding
CHEMBL4482472
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Inhibition of homogeneously purified recombinant Myc bHLH-LZ domain (unknown origin)/Max protein (unknown origin) interaction assessed as reduction in Myc/Max heterodimer formation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent analogues of the c-myc inhibitor 10074-g5 with improved cell permeability
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 4.48 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1336889 | — | — | 1 | 4.48 |
| CHEMBL2312756 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1336889 | — | Kd | = | 33000.0 | nM | 4.48 |
| CHEMBL2312756 | — | Kd | = | 146000.0 | nM | - |