Assay Detail
Functional
CHEMBL4602746
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Antiviral activity against CHIKV
5
Total Activities
5
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pharmaceutical and medicinal significance of sulfur (S<sup>VI</sup>)-Containing motifs for drug discovery: A critical review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.94 | 4.99 |
| IC50 | 1 | 8.82 | 8.82 |
| ED50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2062136 | — | — | 1 | 8.82 |
| CHEMBL4218037 | — | — | 1 | 4.99 |
| CHEMBL4645052 | — | — | 1 | 4.89 |
| CHEMBL4643285 | — | — | 1 | - |
| CHEMBL4647601 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2062136 | — | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL4218037 | — | EC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL4645052 | — | EC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL4643285 | — | EC50 | = | 51.65 | ug.mL-1 | - |
| CHEMBL4647601 | — | ED50 | = | 0.95 | uM | - |