Assay Detail
ADMET
CHEMBL4603064
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human nAChR expressed in human TE671 cells assessed as reduction in nicotine-induced current response by whole-cell patch-clamp method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | TE-671 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Differentiating the Pharmacodynamics and Toxicology of Macrolide and Ketolide Antibiotics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.46 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1136 | TELITHROMYCIN | 4.0 | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1136 | TELITHROMYCIN | IC50 | = | 3500.0 | nM | 5.46 |