Assay Detail
Functional
CHEMBL4604403
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Cytotoxicity against mouse B16F0 cells assessed as reduction in cell viability after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16-F0 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
β,β-Dimethylacrylshikonin Induces Apoptosis in Melanoma Cell Lines by NOXA Upregulation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.72 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267024 | DIMETHYLACRYLSHIKONIN | — | 1 | 5.92 |
| CHEMBL3327388 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267024 | DIMETHYLACRYLSHIKONIN | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL3327388 | — | IC50 | = | 3000.0 | nM | 5.52 |