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Assay Detail

CHEMBL4605115

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against human HS68 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type Hs68
Confidence 1 — Organism
Curated By Autocuration

Target

Hs68 (CHEMBL614578)
Type CELL-LINE
Organism Homo sapiens

Publication

Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein.
Lin CY, Wu HY, Hsu YL, Cheng TR, Liu JH, Huang RJ, Hsiao TH, Wang CJ, Hung PF, Lan A, Pan SH, Chein RJ, Wong CH, Yang PC.
J Med Chem (2020) 63 : 3172 -3187
PubMed 32125853 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.11 7.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4641475 1 7.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4641475 IC50 = 77.0 nM 7.11