Assay Detail
Binding
CHEMBL4606557
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]UR-DE257 from Gsalphas-coupled human recombinant H2R expressed in baculovirus infected Sf9 insect cell membranes
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| pKi | 4 | - | - |
| Ki | 2 | 5.60 | 5.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4642520 | — | — | 1 | 5.74 |
| CHEMBL4635634 | — | — | 1 | 5.45 |
| CHEMBL4640263 | — | — | 1 | - |
| CHEMBL4636487 | — | — | 1 | - |
| CHEMBL4634235 | — | — | 1 | - |
| CHEMBL4646286 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4642520 | — | Ki | = | 1819.7 | nM | 5.74 |
| CHEMBL4635634 | — | Ki | = | 3548.13 | nM | 5.45 |
| CHEMBL4640263 | — | pKi | - | — | - | |
| CHEMBL4636487 | — | pKi | - | — | - | |
| CHEMBL4634235 | — | pKi | - | — | - | |
| CHEMBL4646286 | — | pKi | - | — | - |