Assay Detail
Binding
CHEMBL4610136
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Inhibition of HDAC6 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Histone deacetylase 8 (HDAC8) and its inhibitors with selectivity to other isoforms: An overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.79 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4080014 | — | — | 1 | 8.52 |
| CHEMBL4079541 | — | — | 1 | 6.42 |
| CHEMBL4649745 | — | — | 1 | 6.38 |
| CHEMBL4649617 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4080014 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4079541 | — | IC50 | = | 376.0 | nM | 6.42 |
| CHEMBL4649745 | — | IC50 | = | 417.0 | nM | 6.38 |
| CHEMBL4649617 | — | IC50 | = | 1400.0 | nM | 5.85 |