Assay Detail
Functional
CHEMBL4610550
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human LNCaP-FGC cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP-Clone-FGC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.04 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4633483 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4633483 | — | IC50 | = | 909.5 | nM | 6.04 |