Assay Detail
Functional
CHEMBL4611458
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Neuroprotective activity against sodium arsenite-induced oxidative stress in human astrocytes assessed as reduction in cell death after 20 hrs followed by sodium arsenite addition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Astrocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.29 | 7.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4643134 | — | — | 1 | 7.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4643134 | — | EC50 | = | 51.0 | nM | 7.29 |