Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4611801

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as reduction in microbial growth after incubated for 48 hrs by resazurin dye based assay
4
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Bacillus subtilis
Confidence 1 — Organism
Curated By Autocuration

Target

Bacillus subtilis (CHEMBL359)
Type ORGANISM
Organism Bacillus subtilis

Publication

Talauxins: Hybrid Phenalenone Dimers from <i>Talaromyces stipitatus</i>.
Chaudhary NK, Crombie A, Vuong D, Lacey E, Piggott AM, Karuso P.
J Nat Prod (2020) 83 : 1051 -1060
PubMed 32119543 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.05 6.05
MIC 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL174 AMPICILLIN 4.0 1 6.05
CHEMBL4645427 1 -
CHEMBL4636505 2 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL174 AMPICILLIN IC50 = 900.0 nM 6.05
CHEMBL4645427 IC50 > 200000.0 nM -
CHEMBL4636505 IC50 = 265000.0 nM -
CHEMBL4636505 MIC = 100.0 ug.mL-1 -