Assay Detail
Functional
CHEMBL4611805
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against mouse NS1 cells assessed as reduction in cell viability after 48 hrs by resazurin dye based assay
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Talauxins: Hybrid Phenalenone Dimers from <i>Talaromyces stipitatus</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.75 | 5.34 |
| MIC | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 5.34 |
| CHEMBL4636505 | — | — | 2 | 4.16 |
| CHEMBL4645427 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL4636505 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL4645427 | — | IC50 | = | 140000.0 | nM | - |
| CHEMBL4636505 | — | MIC | = | 25.0 | ug.mL-1 | - |
| CHEMBL4645427 | — | MIC | = | 100.0 | ug.mL-1 | - |