Assay Detail
Binding
CHEMBL4611859
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Inhibition of CDK2 (unknown origin)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
CDK7 Inhibitors in Cancer Therapy: The Sweet Smell of Success?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.42 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4644434 | — | — | 1 | 8.52 |
| CHEMBL4303287 | — | — | 1 | 6.65 |
| CHEMBL4297488 | CT-7001 | 2.0 | 1 | 6.21 |
| CHEMBL1801932 | — | — | 1 | 6.06 |
| CHEMBL4434871 | — | — | 1 | 5.94 |
| CHEMBL4450322 | — | — | 1 | 5.89 |
| CHEMBL4582951 | — | — | 1 | 5.67 |
| CHEMBL4635959 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4644434 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4303287 | — | IC50 | = | 222.0 | nM | 6.65 |
| CHEMBL4297488 | CT-7001 | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL1801932 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL4434871 | — | IC50 | = | 1140.0 | nM | 5.94 |
| CHEMBL4450322 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4582951 | — | IC50 | = | 2117.0 | nM | 5.67 |
| CHEMBL4635959 | — | IC50 | > | 8000.0 | nM | - |