Assay Detail
Binding
CHEMBL4611865
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Inhibition of CDK12 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
CDK7 Inhibitors in Cancer Therapy: The Sweet Smell of Success?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.94 | 6.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4582951 | — | — | 1 | 6.69 |
| CHEMBL3603847 | — | — | 1 | 6.05 |
| CHEMBL4163879 | — | — | 1 | 5.07 |
| CHEMBL4635959 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4582951 | — | IC50 | = | 204.0 | nM | 6.69 |
| CHEMBL3603847 | — | IC50 | = | 893.0 | nM | 6.05 |
| CHEMBL4163879 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL4635959 | — | IC50 | > | 8000.0 | nM | - |