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Assay Detail

CHEMBL4613079

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human Pfeiffer cells incubated for 10 days by WST8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Pfeiffer
Confidence 1 — Organism
Curated By Autocuration

Target

Pfeiffer (CHEMBL4296489)
Type CELL-LINE
Organism Homo sapiens

Publication

EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development.
Rej RK, Wang C, Lu J, Wang M, Petrunak E, Zawacki KP, McEachern D, Fernandez-Salas E, Yang CY, Wang L, Li R, Chinnaswamy K, Wen B, Sun D, Stuckey J, Zhou Y, Chen J, Tang G, Wang S.
J Med Chem (2020) 63 : 7252 -7267
PubMed 32580550 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4104741 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4104741 IC50 = 69.0 nM 7.16