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Assay Detail

CHEMBL4613398

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Functional
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures.
Cheng W, Yang Z, Wang S, Li Y, Wei H, Tian X, Kan Q.
Eur J Med Chem (2019) 164 : 615 -639
PubMed 30639897 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1235529 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1235529 IC50 = 200.0 nM 6.70