Assay Detail
Functional
CHEMBL4613754
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Aurone: A biologically attractive scaffold as anticancer agent.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.88 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1631005 | — | — | 1 | 6.64 |
| CHEMBL4642929 | — | — | 1 | 6.64 |
| CHEMBL326574 | — | — | 1 | 6.60 |
| CHEMBL609865 | — | — | 1 | 4.99 |
| CHEMBL199974 | — | — | 1 | 4.51 |
| CHEMBL4642018 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1631005 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL4642929 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL326574 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL609865 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL199974 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL4642018 | — | IC50 | = | 121900.0 | nM | - |