Assay Detail
Binding
CHEMBL4616552
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Binding affinity to purified integrin alphaVbeta3 receptor (unknown origin) incubated for 2 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Dual Targeting of Norepinephrine Transporter (NET) Function and Thyrointegrin αvβ3 Receptors in the Treatment of Neuroblastoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.60 | 7.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4638793 | — | — | 1 | 7.99 |
| CHEMBL549748 | TETRAC | -1.0 | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4638793 | — | IC50 | = | 10.3 | nM | 7.99 |
| CHEMBL549748 | TETRAC | IC50 | = | 62.4 | nM | 7.21 |