Assay Detail
Functional
CHEMBL4616748
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Antimalarial activity against Plasmodium falciparum K1 by [3H]-hypoxanthine incorporation assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Current scenario of artemisinin and its analogues for antimalarial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 8.27 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4646884 | — | — | 1 | 8.62 |
| CHEMBL4637533 | — | — | 1 | 8.51 |
| CHEMBL4647705 | — | — | 1 | 8.24 |
| CHEMBL4646886 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4646884 | — | EC50 | = | 2.4 | nM | 8.62 |
| CHEMBL4637533 | — | EC50 | = | 3.1 | nM | 8.51 |
| CHEMBL4647705 | — | EC50 | = | 5.8 | nM | 8.24 |
| CHEMBL4646886 | — | EC50 | = | 20.0 | nM | 7.70 |