Assay Detail
Binding
CHEMBL4616965
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Inhibition of bacterial beta-glucuronidase using 4-nitrophenyl beta-D-glucuronopyranoside as substrate
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Therapeutic significance of β-glucuronidase activity and its inhibitors: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.92 | 5.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3785671 | — | — | 1 | 5.67 |
| CHEMBL3786665 | — | — | 1 | 5.38 |
| CHEMBL3785548 | — | — | 1 | 5.20 |
| CHEMBL3787019 | — | — | 1 | 5.14 |
| CHEMBL3787541 | — | — | 1 | 5.05 |
| CHEMBL3785397 | — | — | 1 | 4.81 |
| CHEMBL3787234 | — | — | 1 | 4.78 |
| CHEMBL3786744 | — | — | 1 | 4.72 |
| CHEMBL3786740 | — | — | 1 | 4.65 |
| CHEMBL4641245 | — | — | 1 | 4.51 |
| CHEMBL4642633 | — | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3785671 | — | IC50 | = | 2160.0 | nM | 5.67 |
| CHEMBL3786665 | — | IC50 | = | 4160.0 | nM | 5.38 |
| CHEMBL3785548 | — | IC50 | = | 6280.0 | nM | 5.20 |
| CHEMBL3787019 | — | IC50 | = | 7160.0 | nM | 5.14 |
| CHEMBL3787541 | — | IC50 | = | 8960.0 | nM | 5.05 |
| CHEMBL3785397 | — | IC50 | = | 15610.0 | nM | 4.81 |
| CHEMBL3787234 | — | IC50 | = | 16650.0 | nM | 4.78 |
| CHEMBL3786744 | — | IC50 | = | 19160.0 | nM | 4.72 |
| CHEMBL3786740 | — | IC50 | = | 22610.0 | nM | 4.65 |
| CHEMBL4641245 | — | IC50 | = | 31060.0 | nM | 4.51 |
| CHEMBL4642633 | — | IC50 | = | 60000.0 | nM | 4.22 |