Assay Detail
Binding
CHEMBL4616979
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat liver beta-glucuronidase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic significance of β-glucuronidase activity and its inhibitors: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.13 | 4.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4642119 | — | — | 1 | 4.37 |
| CHEMBL230006 | ENOXOLONE | 2.0 | 1 | 4.01 |
| CHEMBL441687 | GLYCYRRHIZIN | 2.0 | 1 | 4.01 |
| CHEMBL8145 | DAIDZEIN | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4642119 | — | IC50 | = | 42490.0 | nM | 4.37 |
| CHEMBL230006 | ENOXOLONE | IC50 | = | 97210.0 | nM | 4.01 |
| CHEMBL441687 | GLYCYRRHIZIN | IC50 | = | 97210.0 | nM | 4.01 |
| CHEMBL8145 | DAIDZEIN | IC50 | = | 500.0 | ug.mL-1 | - |