Assay Detail
Functional
CHEMBL4617619
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CLR/RAMP1 by cAMP assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Calcitonin-gene-related peptide receptor, CALCRL/RAMP1 (CHEMBL2107838) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Blocking the CGRP Pathway for Acute and Preventive Treatment of Migraine: The Evolution of Success.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.68 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4643006 | — | — | 1 | 11.00 |
| CHEMBL4647045 | — | — | 1 | 10.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4643006 | — | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL4647045 | — | IC50 | = | 0.045 | nM | 10.35 |