Assay Detail
Functional
CHEMBL4618184
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Cytotoxicity against human C4-2 cells transfected with HA-tagged survivin assessed as reduction in cell viability measured after 72 hrs by methylene blue staining based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP C4-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.16 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4635753 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4635753 | — | IC50 | = | 7000.0 | nM | 5.16 |