Assay Detail
Binding
CHEMBL4618858
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Human respiratory syncytial virus A2 Fusion protein expressed in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 4 days by Celltiter-Glo viability assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human respiratory syncytial virus A2 |
| Cell Type | HEp-2 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Fusion glycoprotein F0 (CHEMBL2364165) ↗| Type | SINGLE PROTEIN |
| Organism | Human respiratory syncytial virus |
Publication
Discovery of a Potent Dual Inhibitor of Wild-Type and Mutant Respiratory Syncytial Virus Fusion Proteins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 10.00 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3410450 | PRESATOVIR | 2.0 | 1 | 10.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3410450 | PRESATOVIR | EC50 | = | 0.1 | nM | 10.00 |