Assay Detail
Binding
CHEMBL4619907
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Inhibition of human HDAC6 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structural determinants of affinity and selectivity in the binding of inhibitors to histone deacetylase 6.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.13 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | 1.0 | 1 | 8.30 |
| CHEMBL4066043 | — | — | 1 | 7.25 |
| CHEMBL3040236 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL4066043 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL3040236 | — | IC50 | = | 1400.0 | nM | 5.85 |