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Assay Detail

CHEMBL4620224

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

Design, synthesis & biological evaluation of ferulic acid-based small molecule inhibitors against tumor-associated carbonic anhydrase IX.
Aneja B, Queen A, Khan P, Shamsi F, Hussain A, Hasan P, Rizvi MMA, Daniliuc CG, Alajmi MF, Mohsin M, Hassan MI, Abid M.
Bioorg Med Chem (2020) 28 : 115424 -115424
PubMed 32209296 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.95 4.95

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4640224 1 4.95

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4640224 IC50 = 11220.0 nM 4.95