Assay Detail
Functional
CHEMBL4621284
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Ebola virus 1976 Mayinga infected in African green monkey Vero cells pretreated for 1 hr followed by virus infection measured after 24 hrs by Hoechst staining-based immunofluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Zaire ebolavirus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.55 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4648334 | — | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4648334 | — | EC50 | = | 2830.0 | nM | 5.55 |