Assay Detail
Functional
CHEMBL4621719
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction as Potential Anticancer Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.27 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4646568 | — | — | 1 | 5.36 |
| CHEMBL4646667 | — | — | 1 | 5.18 |
| CHEMBL4646293 | — | — | 1 | - |
| CHEMBL4639202 | — | — | 1 | - |
| CHEMBL4638650 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4646568 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL4646667 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL4646293 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4639202 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4638650 | — | IC50 | > | 10000.0 | nM | - |