Assay Detail
Binding
CHEMBL4621992
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days by crystal violet staining based spectrophotometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bioreducible Phosphonoamidate Pro-drug Inhibitor of Enolase: Proof of Concept Study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.81 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4647008 | — | — | 1 | 6.22 |
| CHEMBL4633981 | — | — | 1 | 5.40 |
| CHEMBL4647387 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4647008 | — | IC50 | = | 604.0 | nM | 6.22 |
| CHEMBL4633981 | — | IC50 | = | 3945.0 | nM | 5.40 |
| CHEMBL4647387 | — | IC50 | > | 100000.0 | nM | - |