Assay Detail
Binding
CHEMBL4621995
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days in presence of 21 % oxygen by crystal violet staining based spectrophotometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bioreducible Phosphonoamidate Pro-drug Inhibitor of Enolase: Proof of Concept Study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.44 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4647008 | — | — | 1 | 6.14 |
| CHEMBL260046 | EVOFOSFAMIDE | 3.0 | 1 | 5.59 |
| CHEMBL4643988 | — | — | 1 | 4.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4647008 | — | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL260046 | EVOFOSFAMIDE | IC50 | = | 2554.0 | nM | 5.59 |
| CHEMBL4643988 | — | IC50 | = | 25887.0 | nM | 4.59 |