Assay Detail
Binding
CHEMBL4622051
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to HIV1 Vif and CBFbeta-ELOB-ELOC complex (unknown origin) by CM5 chip based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Mechanistic Insight into Antiretroviral Potency of 2'-Deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a Long-Lasting Effect on HIV-1 Prevention.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.44 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL519846 | RO-0622 | 3.0 | 1 | 7.06 |
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL519846 | RO-0622 | Kd | = | 87.0 | nM | 7.06 |
| CHEMBL141 | LAMIVUDINE | Kd | = | 1510.0 | nM | 5.82 |