Assay Detail
Binding
CHEMBL4622300
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Binding affinity to sigma 2 receptor (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Exploration of Alternative Scaffolds for P2Y<sub>14</sub> Receptor Antagonists Containing a Biaryl Core.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.83 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4637158 | — | — | 1 | 6.52 |
| CHEMBL4640370 | — | — | 1 | 6.38 |
| CHEMBL4646514 | — | — | 1 | 5.86 |
| CHEMBL4633982 | — | — | 1 | 5.68 |
| CHEMBL4645216 | — | — | 1 | 5.64 |
| CHEMBL4642215 | — | — | 1 | 5.54 |
| CHEMBL4645987 | — | — | 1 | 5.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4637158 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL4640370 | — | Ki | = | 420.0 | nM | 6.38 |
| CHEMBL4646514 | — | Ki | = | 1370.0 | nM | 5.86 |
| CHEMBL4633982 | — | Ki | = | 2090.0 | nM | 5.68 |
| CHEMBL4645216 | — | Ki | = | 2290.0 | nM | 5.64 |
| CHEMBL4642215 | — | Ki | = | 2910.0 | nM | 5.54 |
| CHEMBL4645987 | — | Ki | = | 6700.0 | nM | 5.17 |