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Assay Detail

CHEMBL4623308

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibition of CYP450 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Cytochrome P450 (CHEMBL4523986)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators.
Chen Y, Li Q, Li Q, Xing S, Liu Y, Liu Y, Chen Y, Liu W, Feng F, Sun H.
J Med Chem (2020) 63 : 10135 -10157
PubMed 32324396 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.72 4.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL347036 PROADIFEN HYDROCHLORIDE -1.0 1 4.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL347036 PROADIFEN HYDROCHLORIDE IC50 = 19000.0 nM 4.72