Assay Detail
Binding
CHEMBL4623703
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Inhibition of calf intestinal alkaline phosphatase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
An efficient synthetic approach toward a sporadic heterocyclic scaffold: 1,3-Oxathiol-2-ylidenes; alkaline phosphatase inhibition and molecular docking studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.44 | 6.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4643990 | — | — | 1 | 6.17 |
| CHEMBL4637195 | — | — | 1 | 5.94 |
| CHEMBL4643304 | — | — | 1 | 5.54 |
| CHEMBL301523 | PHENYLALANINE | 3.0 | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4643990 | — | IC50 | = | 670.0 | nM | 6.17 |
| CHEMBL4637195 | — | IC50 | = | 1160.0 | nM | 5.94 |
| CHEMBL4643304 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL301523 | PHENYLALANINE | IC50 | = | 80210.0 | nM | 4.10 |